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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDR2
All Species:
19.09
Human Site:
S452
Identified Species:
32.31
UniProt:
Q16832
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16832
NP_001014796.1
855
96736
S452
L
S
L
P
S
D
S
S
M
F
N
N
N
R
S
Chimpanzee
Pan troglodytes
Q7YR43
909
100624
I466
L
S
V
P
G
D
T
I
L
I
N
N
R
P
G
Rhesus Macaque
Macaca mulatta
XP_001118206
855
96702
S452
L
S
L
P
S
D
S
S
M
F
N
N
N
R
S
Dog
Lupus familis
XP_536144
849
95798
S446
L
S
L
P
S
E
S
S
M
F
N
N
N
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62371
854
96464
S452
L
S
L
P
S
E
S
S
M
F
N
N
N
R
S
Rat
Rattus norvegicus
Q63474
910
101146
I467
L
S
V
P
G
D
T
I
L
I
N
N
R
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515915
914
101965
M501
S
L
P
S
E
S
S
M
Y
N
H
H
R
R
S
Chicken
Gallus gallus
Q91987
818
91718
G404
E
T
T
P
N
D
L
G
D
T
T
N
N
S
N
Frog
Xenopus laevis
O73798
1358
153845
K749
S
T
V
T
S
Y
E
K
N
S
T
T
E
D
F
Zebra Danio
Brachydanio rerio
XP_684261
892
101731
Y487
I
Q
S
E
T
F
T
Y
N
N
N
N
S
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24488
685
78124
L327
G
T
T
A
A
I
I
L
I
F
I
I
I
F
A
Honey Bee
Apis mellifera
XP_392450
898
100991
S461
L
T
M
E
Q
F
N
S
P
L
V
S
P
Q
Y
Nematode Worm
Caenorhab. elegans
NP_508572
797
90284
P420
V
K
A
S
S
P
S
P
N
A
K
R
E
I
L
Sea Urchin
Strong. purpuratus
XP_001202828
913
103393
T485
N
C
N
G
G
G
A
T
I
N
N
C
P
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
99.3
96.4
N.A.
95.9
52.8
N.A.
80.1
27.1
21
74.5
N.A.
24.3
30.2
32.8
39.8
Protein Similarity:
100
66
99.5
97.8
N.A.
97.3
66.1
N.A.
85.8
42.8
34.3
82.6
N.A.
41.9
48.7
52
55
P-Site Identity:
100
40
100
93.3
N.A.
93.3
40
N.A.
20
26.6
6.6
20
N.A.
6.6
13.3
13.3
6.6
P-Site Similarity:
100
60
100
100
N.A.
100
60
N.A.
33.3
46.6
20
46.6
N.A.
33.3
46.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
8
0
0
8
0
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
36
0
0
8
0
0
0
0
8
0
% D
% Glu:
8
0
0
15
8
15
8
0
0
0
0
0
15
0
0
% E
% Phe:
0
0
0
0
0
15
0
0
0
36
0
0
0
8
8
% F
% Gly:
8
0
0
8
22
8
0
8
0
0
0
0
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
8
0
0
0
0
8
8
15
15
15
8
8
8
8
8
% I
% Lys:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% K
% Leu:
50
8
29
0
0
0
8
8
15
8
0
0
0
0
8
% L
% Met:
0
0
8
0
0
0
0
8
29
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
8
0
8
0
22
22
58
58
36
0
8
% N
% Pro:
0
0
8
50
0
8
0
8
8
0
0
0
15
22
0
% P
% Gln:
0
8
0
0
8
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
22
36
0
% R
% Ser:
15
43
8
15
43
8
43
36
0
8
0
8
8
8
43
% S
% Thr:
0
29
15
8
8
0
22
8
0
8
15
8
0
8
0
% T
% Val:
8
0
22
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _